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AM - 上海硅酸盐所施剑林研究员、步文博研究员

发布时间: 2014-6-18 来源: WILEY-VCH


Title: Nanodots: Ultrasmall NaGdF4 Nanodots for Efficient MR Angiography and Atherosclerotic Plaque Imaging

Abstract: As shown by J. Shi, W. Bu, and co‐workers on page 3867, ultrasmall NaGdF4 nanodots (ca. 2 nm) with diethylenetriaminepenta‐acetic acid (DTPA) conjugation are synthesized for efficient magnetic resonance (MR) angiography. Impressively, the r1 value in magnetic resonance imaging (MRI) reaches up to 8.93 mM−1 s−1. The ultrasmall vessel lumen of a rabbit is lit up remarkably. After 3 h, atherosclerotic plaques can be discriminated clearly. This is quite favorable for the accurate early diagnosis of vascular pathema.


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